POLYDATIN INHIBITS HEPATOCELLULAR CARCINOMA VIA THE AKT/STAT3‑FOXO1 SIGNALING PATHWAY

POLYDATIN INHIBITS HEPATOCELLULAR CARCINOMA VIA THE AKT/STAT3‑FOXO1 SIGNALING PATHWAY
Polydatin, extracted from Polygonum cuspidatum, is known for its anti‑platelet aggregation and anti‑inflammatory effects. However, studies on the association of polydatin with cancer are limited, particularly with regards to epithelial‑mesenchymal transition (EMT)‑associated migration and invasion of cancer cells. The purpose of the present study was to reveal the potential anticancer effects of polydatin on hepatocellular carcinoma (HCC) cells, particularly its effects on EMT….

 

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